Migraine without aura
Conditions
Interventions
MRI-guided scalp acupuncture group:MRI scalp acupuncture for Migraine
Non-needle non-acupoint group:non-acupoints acupuncture
Traditional acupoint group:Traditional acupuncture point needling scheme
Sponsors
Guang’anmen Hospital, China academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as migraine without aura using the criteria defined in ICHD-3; 2. Age between 18 and 65 years old, right-handed, gender not limited; 3. Diagnosed with migraine for more than 1 year, free from preventive treatment drugs for migraine within 3 months before enrollment (emergency pain-relieving drugs are allowed), and no acupuncture therapy within 1 month before enrollment; 4. No contraindications for MRI examination (such as cardiac pacemaker, implanted metal devices, etc.), and able to tolerate a 20-minute MRI examination; 5. Voluntarily agree to participate in this study with written informed consent provided.
Exclusion criteria
Exclusion criteria: 1.Tension-type headache, cluster headache, and other primary headaches as well as trigeminal neuralgia; 2. Secondary headaches caused by hypertension, brain trauma, intracranial lesions, or other definite causes (such as alcohol withdrawal, drug withdrawal), etc.; 3. Pregnancy, lactation, or women of childbearing potential without contraception; 4. Significant organ dysfunction such as cardiac, hepatic, or renal impairment; uncontrolled blood sugar or blood pressure; severe anxiety or depression; other investigator-determined clinical ineligibility; 5. Use of psychotropic medications (anxiolytics/antidepressants/antipsychotics) within 3 months prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Days of migraine attack;Frequency of migraine attacks; | — |
Secondary
| Measure | Time frame |
|---|---|
| Days of migraine attack;Frequency of migraine attacks;Headache severity;Headache diary;Migraine Specific Quality of Life Questionnaire;Hamilton Anxiety Rating Scale;Hamilton Depression Rating Scale; | — |
Countries
China
Contacts
Public ContactBinlong Zhang
Guang’anmen Hospital, China academy of Chinese Medical Sciences
Outcome results
None listed