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The study on the minimum effective dose (MEC90) of bupivacaine liposome for post-cesarean section analgesia.

The study on the minimum effective dose (MEC90) of bupivacaine liposome for post-cesarean section analgesia.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101553
Enrollment
Unknown
Registered
2025-04-27
Start date
2025-05-28
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postsurgical pain

Interventions

Experimental Group:Perform ultrasound-guided quadratus lumborum block using liposomal bupivacaine

Sponsors

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1.Patients scheduled to undergo elective cesarean section at the Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University. 2.Age between 18 and 40 years. 3.American Society of Anesthesiologists (ASA) physical status classification of I-II. 4.Body weight between 60 and 80 kg.

Exclusion criteria

Exclusion criteria: 1. Refusing to participate in a study 2. Allergic to local anesthetics 3. Previous neuropathy 4. Coagulation dysfunction (platelets should be >= 80×10^9 /L) 5. High-risk pregnancy

Design outcomes

Primary

MeasureTime frame
VAS pain score (resting and activity) (at each observation point);Total opioid consumption(at each observation point);

Secondary

MeasureTime frame
Recovery of gastrointestinal function;Time to first ambulation;Postoperative recovery rate;Bupivacaine blood concentration;

Countries

China

Contacts

Public ContactZhang Ying

Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University

zhangying021210@163.com+86 135 5172 0908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026