Chronic Atrophic Gastritis associated with Helicobacter pylori infection.
Conditions
Interventions
Gold Standard:Gastroduodenoscopy combined with pathological biopsy is used as the gold standard for the diagnosis of chronic atrophic gastritis.
Index test:The deep convolutional neural network model diagnoses chronic atrophic gastritis using endoscopic and pathological images.
Sponsors
Xi'an Jiaotong University Second Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 89 Years
Inclusion criteria
Inclusion criteria: 1.Individuals undergoing gastroscopy at designated hospitals; 2.Written consent for participation in this study; 3.Clear and complete gastroscopy report results; 4.Clear status of Helicobacter pylori infection;
Exclusion criteria
Exclusion criteria: 1.Severe brain, liver, heart, and lung dysfunction; 2.End-stage renal disease requiring dialysis; 3.Schizophrenia or other mental illnesses that hinder patient cooperation; 4.Pregnancy; 5.Pyloric obstruction; 6.Inadequately prepared patients (excessive food residue interfering with endoscopy); 7.Antibiotics or proton-pump inhibitors (PPI) were used for 4 weeks before study initiation; 8.Previous diagnosis was early or advanced gastric cancer; 9.After gastrectomy; 10.Tendency to bleed;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The sensitivity and specificity of the model in diagnosing chronic atrophic gastritis.;Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| The crypt depth becomes shallower or deeper;The inter-crypt distance becomes larger or smaller;Positive or negative for Helicobacter pylori infection;The orifice diameter becomes larger or smaller; | — |
Countries
China
Contacts
Public ContactQin Bin
Xi'an Jiaotong University Second Affiliated Hospital
Outcome results
None listed