Functional Gastrointestinal Disorders (FGIDs)
Conditions
Interventions
Experimental group:A total of 60 subjects took 2 packages of normal temperature long shelf life yogurt (subject A) with Ilamoxi probiotics (containing LGG active probiotics) every day, 200g/ package,
Control group 1:A total of 60 subjects were given 2 packages of 200g/ package of ordinary normal temperature long shelf life yogurt (subject B) without LGG active probiotics every day. Lactobacillus b
Control group 1:A total of 60 subjects took 2 packs of 200g/ pack of acid-adjusted milk (subject C) every day, which was a non-commercially available product provided by Yili that had passed the test
Sponsors
Peking University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old; 2. In the past six months, there are symptoms of functional gastrointestinal disorders, such as functional dyspepsia, the main complaint of long-term gastrointestinal discomfort, loss of appetite, early satiety, excessive gas, gastrointestinal distention, vomiting, unexplained chronic diarrhea or constipation, etc., and the symptoms are mild and do not need to be relieved by medication; 3. Antibiotics, prebiotics/probiotics, nutrient supplements and other drugs/foods that may affect the study results have not been used within 1 month before the study; 4. Did not participate in other clinical studies within 1 month before the study; 5. Agree not to take antibiotics, prebiotics/probiotics, nutrient supplements and other drugs/foods that may affect the study results during the study period; 6. Agree not to take other types of fermented dairy products and acid-adjusted milk during the study period; 7. Agree not to participate in other clinical studies during the study period; 8. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Being treated for gastrointestinal symptoms (such as laxatives),or acute diarrhea sufferers. 2. There is lactose intolerance; 3. There is serious digestive disease (such as peptic ulcer, inflammatory bowel disease, pancreatitis, cirrhosis, gastrointestinal resection history, etc.); 4. There is infectious disease or other serious physical disease (such as severe infection, acute myocardial infarction, cardiac insufficiency, renal insufficiency, stroke, hyperthyroidism, tumor, immune deficiency, physical disability, etc.) or mental illness; 5. Women who are pregnant or breastfeeding, or who plan to become pregnant during the study period. 6. During the study period, failure to take the test samples as required may affect the interpretation of the results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fecal pH;Fecal sIgA;Fecal calprotectin;Fecal a 1-antitrypsin;Fecal SCFAs;Fecal lactic acid;Fecal secondary bile acids;FBG;Serum Insulin;HbA1c;Serum TC;Serum TG;Serum HDL-C;Serum LDL-C;Serum VLDL-C;Serum transaminase;Serum creatinine; | — |
Countries
China
Contacts
Public ContactJiang Hua
School of Nursing, Peking University
Outcome results
None listed