Periodontitis
Conditions
Interventions
II stage Periodontitis group:Supringival scaling + subgingival scaling
III stage Periodontitis group:Supringival scaling + subgingival scaling
I stage Periodontitis group:Supringival scaling + subgingival scaling
IV stage Periodontitis group:Supringival scaling + subgingival scaling
Sponsors
The First Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. The healthy control group was included: (1) there was no significant change in gingival color, no inflammation, no change in texture, and no other abnormal symptoms; (3) Plaque index (PLI) 1, (2) plaque index (PLI) >1, (3) attachment loss (AL) >=3mm; (4) Probing depth (PD) >=4mm; (5) Radiographic alveolar bone resorption; (6) Periodontitis patients aged 18 years < age < 55 years old. According to the new classification and diagnostic criteria for periodontitis proposed at the 2017 AAP and EAP World Symposiums, periodontitis was divided into patients with stage I, II, III and IV periodontitis.
Exclusion criteria
Exclusion criteria: 1. Patients who have received periodontal treatment in the past 12 months; (2) patients who have received medication in the past 6 months; (3) Patients with systemic diseases, psychiatric disorders, pregnancy or lactation, and other oral diseases that may affect periodontal conditions; (4) Body mass index BMI>=28.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| D-dimer;Thrombine-antithrombin complex;Changes of serum differential protein expression;Detection of oral subgingival microbial characteristics;Changes of serum metabolites;Fibrinogen;Tissue plasminogen activator-plasminogen activator-1 complex;Thrombin time;Prothrombin time;Activated partial thrombin time; | — |
Countries
China
Contacts
Public ContactChen Xi
The First Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed