Skip to content

Application of modified transversus abdominis plane block (M-TAPA) via the perichondrial approach under ultrasound guidance in pain after robot-assisted radical prostatectomy: A clinical three-arm randomized controlled study

Application of modified transversus abdominis plane block (M-TAPA) via the perichondrial approach under ultrasound guidance in pain after robot-assisted radical prostatectomy: A clinical three-arm randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101467
Enrollment
Unknown
Registered
2025-04-25
Start date
2025-05-14
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain after robot - assisted radical prostatectomy

Interventions

Group M-TAPA:Patients underwent bilateral ultrasound-guided transperichondral modified thoracoabdominal nerve block 30min preoperatively with 0.375% ropivacaine as local anesthetic with a total volume
Group PCIA:Postoperatively, patients were treated with intravenous self-controlled analgesia (PCIA), morphine 0.5mg/kg/d ondansetron hydrochloride injection 8mg, diluted with 0.9% sodium chloride inje
Group QLB:The patient underwent bilateral ultrasound-guided anterior quadratus lumbar muscle block 30min preoperatively with 0.375% ropivacaine as local anesthetic with a total volume of 40ml. Postope

Sponsors

The First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Adult patients aged 18 - 80 years old; 2.ASA I~III; 3.Plan to undergo elective robot - assisted radical prostatectomy under general anesthesia;

Exclusion criteria

Exclusion criteria: Contraindications to peripheral nerve blocks (local or systemic infection; pre-existing neurological deficits or neuropathy); Any psychiatric or psychiatric illness that precludes the assessment; hypersensitivity to analgesic regimens or any component of local anesthesia; or chronic opioid use (preoperative >=4 weeks, daily morphine consumption dose >=30mg); suffering from chronic pain; People with severe cardiac, hepatic, renal disease, and alcohol and drug dependence are contraindicated for regional anesthesia (cardiac function index up to class III. or IV., LVEF3 times the upper limit of normal, serum albumin 1.5; renal function indexes: glomerular filtration rate 265 µmol/L (males) or > 221 µmol/L (females), urea nitrogen BUN> 21.4 mmol/L, urinary examination showed massive proteinuria or severe hematuria).

Design outcomes

Primary

MeasureTime frame
The morphine consumption within 24 hours;

Countries

China

Contacts

Public ContactQuanguang Wang

The First Affiliated Hospital of Wenzhou Medical University

quanguangwang@wzhospital.cn+86 13736935500

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026