Coronary artery disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) age >= 18 years; (2) suspected CAD; (3) provision of written informed consent.
Exclusion criteria
Exclusion criteria: (1) contraindication to iodinated contrast agents, including hypersensitivity reactions, renal insufficiency (glomerular filtration rate < 45 mL/min per m2), hyperthyroidism; (2) contraindication to glyceryl trinitrates and beta-blockers, including glaucoma, and hypotension (blood pressure < 90/60mmHg); (3) severe arrhythmias that may compromise coronary CT image quality, such as sustained atrial fibrillation, second-degree or third-degree atrioventricular block, left bundle branch block, sinus arrhythmia, and pre-excitation syndrome; (4) target heart rate reduction (<= 65 beats per minute) was not achieved despite maximal tolerated doses of oral beta-blockers and subsequent dose adjustments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of coronary high risk plaques ; | — |
Secondary
| Measure | Time frame |
|---|---|
| The agreement of radiologists' evaluation of coronary artery stenosis;The agreement between the evaluation of coronary artery stenosis by AI and that by radiologists;Coronary wall sharpness;Signal-to-noise ratio of coronary artery ; | — |
Countries
China
Contacts
Jiangsu Province Official Hospital (Geriatric Hospital of Nanjing Medical University)