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Study on Coronary Angiography Using Photon Counting Computed Tomography

Study on Coronary Angiography Using Photon Counting Computed Tomography

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101458
Enrollment
Unknown
Registered
2025-04-25
Start date
2025-05-05
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

Ultra-high resolution group:Subjects who underwent coronary CT angiography were scanned with ultra-high resolution
Standard resolution group:Subjects who underwent coronary CT angiography were scanned with standard resolution

Sponsors

Jiangsu Province Official Hospital (Geriatric Hospital of Nanjing Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) age >= 18 years; (2) suspected CAD; (3) provision of written informed consent.

Exclusion criteria

Exclusion criteria: (1) contraindication to iodinated contrast agents, including hypersensitivity reactions, renal insufficiency (glomerular filtration rate < 45 mL/min per m2), hyperthyroidism; (2) contraindication to glyceryl trinitrates and beta-blockers, including glaucoma, and hypotension (blood pressure < 90/60mmHg); (3) severe arrhythmias that may compromise coronary CT image quality, such as sustained atrial fibrillation, second-degree or third-degree atrioventricular block, left bundle branch block, sinus arrhythmia, and pre-excitation syndrome; (4) target heart rate reduction (<= 65 beats per minute) was not achieved despite maximal tolerated doses of oral beta-blockers and subsequent dose adjustments.

Design outcomes

Primary

MeasureTime frame
Detection rate of coronary high risk plaques ;

Secondary

MeasureTime frame
The agreement of radiologists' evaluation of coronary artery stenosis;The agreement between the evaluation of coronary artery stenosis by AI and that by radiologists;Coronary wall sharpness;Signal-to-noise ratio of coronary artery ;

Countries

China

Contacts

Public ContactYong Yuan

Jiangsu Province Official Hospital (Geriatric Hospital of Nanjing Medical University)

53615238@qq.com+86 136 5516 3572

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026