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Screening of diagnostic markers for immune-related adverse reactions in liver cancer based on proteomics

Screening of diagnostic markers for immune-related adverse reactions in liver cancer based on proteomics

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101449
Enrollment
Unknown
Registered
2025-04-25
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A series of adverse reactions occurred in liver cancer patients receiving immunotherapy.

Interventions

Small sample screening(Low-risk and high-risk groups):None
Multi-center validation(Low-risk and high-risk groups):None

Sponsors

The Seventh Affiliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged 18 or older; 2.Patients with CNLC ?a or ?b liver cancer; 3.Patients with CNLC ?b liver cancer not suitable for surgical resection or TACE; 4.Patients with liver cancer resistant to or failed TACE; 5.Patients about to receive immune checkpoint inhibitor therapy; 6.No immunodeficiency, such as HIV infection, leukemia, or neutropenia; 7.No history of organ or bone marrow transplantation (autologous bone marrow suppression excluded); 8.No concurrent viral, bacterial, or other pathogen infections; 9.Written informed consent obtained; patient agrees to participate in the study.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

MeasureTime frame
Adverse effects;

Countries

China

Contacts

Public ContactShuo Fang

The Seventh Affiliated Hospital Sun Yat-sen University

vickyfs@126.com+86 755 81206796

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026