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A study of the effectiveness of pressurized hypothermia in improving paclitaxel combined with platinum-associated peripheral neuropathy in lung cancer patients

A study of the effectiveness of pressurized hypothermia in improving paclitaxel combined with platinum-associated peripheral neuropathy in lung cancer patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101439
Enrollment
Unknown
Registered
2025-04-24
Start date
2025-04-24
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

intervention group:The intervention group added pressurized cryotherapy therapy on the basis of conventional treatment and conventional nursing care, which was operated as follows:(1)A research team w
control subjects:The control group implemented conventional treatment and routine nursing measures, the specific methods are as follows: (1) admission counseling, inform the chemotherapy precautions a

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Pathological diagnosis of malignant tumor; (2) Age 18 ~75 years old; (3) Chemotherapy regimen containing paclitaxel and platinum drugs; (4) High compliance and completion of the chemotherapy program; (5) Good cooperation and self-completion of all questionnaires in this study.

Exclusion criteria

Exclusion criteria: (1) Combination of severe underlying diseases of the brain, kidney and liver; (2) Expected survival period is less than 6 months; (3) Combination of diabetic peripheral neuropathy, Raynaud's syndrome, fibromyalgia and so on.

Design outcomes

Primary

MeasureTime frame
FACT/GOG-Ntx Neurotoxicity Assessment Tool Scale;EORTC QLQ-C30 Quality of Life;

Secondary

MeasureTime frame
Cryotherapy Treatment Tolerance;

Countries

China

Contacts

Public ContactQian Zhang

West China hospital sichuan university

zhangqian6361@wchscu.cn+86 130 3567 7168

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026