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The Plasma Concentration of Bictegravir/Emtricitabine/Tenofovir Alafenamide and Influencing Factors in Low-Level Viremia among PLWH in Sichuan: A Prospective Observational Study

The Plasma Concentration of Bictegravir/Emtricitabine/Tenofovir Alafenamide and Influencing Factors in PLWH with low-level viremia in Sichuan: A Prospective Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101438
Enrollment
Unknown
Registered
2025-04-24
Start date
2025-05-10
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV

Interventions

PLWH with LLV:None

Sponsors

The Public Health Clinical Center of Chengdu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosised with HIV infection; 2. Over 18 years or above; 3. Taking BIC/FTC/TAF for more than 6 months; 4. HIV-RNA levels was between 50 copies/ml and 200 copies/ml for two consecutive times; 5. Capable of understanding and providing written informed consent; 6. Demonstrates good compliance and is able to cooperate in completing all required examinations and follow-ups during the study period.

Exclusion criteria

Exclusion criteria: 1.Irregular use, discontinuation or cessation of BIC/FTC/TAF 2.Pregnant women, history of organ transplantation, active malignant tumors, opportunistic infection, or other severe complications. 3. Anticipated receipt of immunosuppressive therapy, chemotherapy or continuous steroid therapy during the study period. 4. Patients with unstable mental states or cognitive impairments. 5. Any other conditions deemed unsuitable for study participation by the investigator.

Design outcomes

Primary

MeasureTime frame
Complete Blood Count ;Blood biochemistry;T-Lymphocyte Count;HIV-RNA Viral Load;plasma concentration of BIC/FTC/TAF;

Countries

China

Contacts

Public ContactDongmei Yan

The Public Health Clinical Center of Chengdu

15982491863@163.com+86 159 8249 1863

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026