Frailty
Conditions
Interventions
Group C (the conventional PSA group):Choose the conventional procedure for sedation and analgesia (PSA) to perform a painless colonoscopy (i.e., fentanyl 0.5 micrograms per kilogram + propofol 1-2 mil
Group R (the awake sedation group):Choose the awake sedation anesthesia technique for performing painless colonoscopy (i.e., fentanyl 0.5 micrograms/kg + remimazolam0.1-0.3 milligrams/kg)
Sponsors
Xuyi People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. American society of anesthesiology (ASA) classification I.~III.; 2. Age greater than or equal to 65 years old; 3. Patients who intend to undergo painless colonoscopy in the outpatient clinic.
Exclusion criteria
Exclusion criteria: 1. Those who suffer from mental illness or are unable to communicate verbally; 2. Amputee patients; 3. Paraplegic patients; 4. Pre-existing chronic pain, long-term treatment with painkillers; 5.BMI>40 kg/m^2 ; 6. Psychiatric or neurological disorders; 7. Patients with severe liver and kidney insufficiency, respiratory system and cardiovascular and cerebrovascular diseases before surgery; 8. Allergy to local anesthetics or sedative analgesics; 9. Refusal to Participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and duration of hypotension ; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence and duration of hypoxemia;The incidence of injection pain;The incidence of respiratory depression;Incidence of nausea and vomiting;Recovery time;Discharge Time from Recovery Room; RASS Sedation Score;Modified FRAIL Frailty Scale score; | — |
Countries
China
Contacts
Public ContactChai Xiaoming
Xuyi People's Hospital
Outcome results
None listed