Major Depression
Conditions
Interventions
Gold Standard:Subjects who met the diagnosis of depression were first initially screened by the Mini International Neuropsychiatric Interview, M.I.N.I., ver. 7.0.2 (M.I.N.I., ver. 7.0.2). Subsequently
Index test:HAMD Scale and BDI Scale
Sponsors
The Fourth People's Hospital of Hefei
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Depression group: firstly, through the Mini International Neuropsychiatric Interview (M.I.N.I., ver. 7.0.2) Preliminary screening of subjects who meet the diagnosis of depression. Subsequently, the patients were evaluated in detail using the HAMD Other Rating Scale and the BDI Self-Rating Scale, and the subtype of the patient was determined according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). This study plans to recruit four subtypes of depression diagnosed by DSM-5: typical, atypical, seasonal, and melancholic. The requirements for recruitment include: gender is not limited, right-handed, age 18-65 years old, primary school education level or above, no serious physical illness or other mental disorders; (2) Healthy control group: Healthy individuals matched to the depression group in age and gender were recruited, and no mental disorder was diagnosed with M.I.N.I. scale assessment, normal results of HAMD and BDI scales, and no history of mental disorders. At the same time, the subjects in the depression group and the healthy control group had normal unaided or corrected visual acuity (no less than 0.2 logMAR) and no visual field defects. All participants or their legal guardians are required to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients who have received antidepressant treatment recently (within 6 months); 2.individuals with a history of severe neurological diseases or other mental illnesses; 3.individuals with a history of substance abuse; 4.and subjects who do not meet the enrollment criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non-linear characteristic;Linear characteristic; | — |
Countries
China
Contacts
Public ContactHe Chen
The Fourth People's Hospital of Hefei
Outcome results
None listed