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Efficacy and safety of adjuvant chemotherapy after radical surgery for intrahepatic cholangiocarcinoma: a multi-center retrospective study in China

Efficacy and safety of adjuvant chemotherapy after radical surgery for intrahepatic cholangiocarcinoma: a multi-center retrospective study in China

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101407
Enrollment
Unknown
Registered
2025-04-24
Start date
2025-04-25
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrahepatic cholangiocarcinoma

Interventions

Postoperative observation group:None

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Undergo radical resection for liver cance; 2. It was diagnosed as intrahepatic cholangiocarcinoma by postoperative pathological examination; 3. Has not received any other systemic treatment or surgical treatment for liver cancer;

Exclusion criteria

Exclusion criteria: 1. Non-radical resection (pathologically confirmed positive resection margin); 2. Perioperative death; 3. Combined with other malignant tumors; 4. Recurrent ICC;

Design outcomes

Primary

MeasureTime frame
Overall survival , OS;

Secondary

MeasureTime frame
Adverse events, AE;Progression-free survival, PFS;Serious adverse events, SAE;Carcinoembryonic antigen, CEA;Aspartate aminotransferase, AST;Alanine aminotransferase, ALT;CA19-9;ALB;Total bilirubin, TBIL;Alkaline phosphatase, ALP;

Countries

China

Contacts

Public ContactXin Zheng

The First Affiliated Hospital of Xi'an Jiaotong University

zhengxin@xjtufh.edu.cn+86 29 85323215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026