Head tumours/strokes, abdominal organ lesions, knee injuries, ankle trauma
Conditions
Interventions
Internal Validation group :none
External Validation group :none
Sponsors
Changhai Hospital, The Navy Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Clinical Indications - Patients with clinically indicated MRI requisitions for targeted anatomical regions (disease group) - Healthy volunteers meeting study enrollment criteria with voluntary participation (health group) (2) Technical Feasibility - Capacity to complete dual-protocol MRI acquisitions: ? Standard clinical scanning protocol ? Motion-artifact induced scanning protocol (Use of FDA-approved artefact simulation devices) (3) Ethical Compliance - Signed dynamic electronic informed consent (DEIC) with blockchain-based audit trail(Deposit of evidence via blockchain) - Exclusion of concurrent enrollment in other imaging trials (Elution period >= 3 months)
Exclusion criteria
Exclusion criteria: (1) Safety Contraindications(excluded if any one of them is satisfied): - Absolute MRI contraindications (e.g., cardiac pacemakers/magnetic implants). - Pregnancy(admission permitted only with negative blood ß-hCG test). (2) Technical Limitations: - Body Mass Index (BMI) >=40 (due to scanning bore limitations). - Metallic implants in the target area (Artifact Reduction Score = 20). - Life expectancy < 6 months (for palliative care patients).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consistency in Lesion Detection;Diagnostic Confidence Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Contrast-to-Noise Ratio;Signal-to-Noise Ratio;Peak Signal-to-Noise Ratio;Mean Structural Similarity Index Measure; | — |
Countries
China
Contacts
Public ContactYun Bian
Changhai Hospital, The Navy Military Medical University
Outcome results
None listed