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A randomized controlled trial of single anticoagulant therapy before hepatectomy for the prevention of ultra-early postoperative deep venous thrombosis of lower limbs

A randomized controlled trial of single anticoagulant therapy before hepatectomy for the prevention of ultra-early postoperative deep venous thrombosis of lower limbs

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101395
Enrollment
Unknown
Registered
2025-04-24
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative deep venous thrombosis of lower limbs

Interventions

The group with combined drug and mechanical prophylaxis:Enoxaparin Sodium Injection
The group with pure mechanical prophylaxis:Intraoperative pneumatic therapy

Sponsors

The First Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily participate in this study and sign the informed consent form; 2. Patients are over 18 years old, regardless of gender; 3. Patients who need to undergo hepatectomy due to liver tumors;

Exclusion criteria

Exclusion criteria: 1. Patients who have used anticoagulant drugs (heparin, low - molecular - weight heparin, warfarin, or other oral anticoagulants) within 30 days before the operation; 2. Patients with a history of deep vein thrombosis (DVT); 3. Patients with thrombosis in both lower - limb veins as indicated by preoperative color ultrasound; 4. Patients who did not undergo physical prophylaxis during surgery; 5. For the intervention drug (Keselmine) or the presence of other contraindications to its use.

Design outcomes

Primary

MeasureTime frame
Lower limb deep vein thrombosis after hepatectomy;

Secondary

MeasureTime frame
Safety;

Countries

China

Contacts

Public ContactSun xiaodong

The First Hospital of Jilin University

sxd@jlu.edu.cn+86 431 8878 5162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026