Postoperative nausea and vomiting
Conditions
Interventions
Penehyclidine group:Before anesthesia induction, flurbiprofen cilexil 50 mg, dexamethasone 5 mg, and pentethylquine 0.5 mg were administered
Droperidol group:Flurbiprofen cilexil 50 mg, dexamethasone 5 mg, and droperidol 5 mg were given before anesthesia induction
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Females aged 18-65 years; 2. ASAI-II; 3. Body mass index (BMI) 18.5-27.9kg/m^2; 4. Patients who are expected to undergo gynecological day surgery; 5. Patients should have a detailed understanding of the nature, significance, possible benefits, possible inconveniences and potential dangers of the trial before the trial, understand the research procedures and voluntarily sign the informed consent form in writing.
Exclusion criteria
Exclusion criteria: 1. Patients with obvious respiratory and circulatory dysfunction, abnormal liver and kidney function before surgery; 2. Those who are allergic or contraindicated to the drugs used in the study; 3. The operation time is more than 1 hour; 4. Those who cannot understand or refuse to complete the questionnaire; 5. Patients who are unable to obtain informed consent, or who are considered by the investigator to be inappropriate to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PONV within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of PONV in PACU;Severity of PONV within 24 hours postoperatively;Adverse reactions during anesthesia induction;Time to fall asleep;Intraoperative adverse reactions;Time of resuscitation;Adverse reactions within PACU; | — |
Countries
China
Contacts
Public ContactFanceng Ji
Weifang People's Hospital, Shandong Province
Outcome results
None listed