Colorectal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. All participants signed the informed consent form; 2. Age range: 45 - 75 years old; 3. American Society of Anesthesiologists (ASA) classification: I - III; 4. Scheduled for laparoscopic radical resection of colorectal cancer, with operation duration >= 120 minutes; 5. Preoperative Barthel Index score >= 95 points.
Exclusion criteria
Exclusion criteria: 1. Patients with mental and psychological disorders; 2. Those with a history of long-term alcohol abuse and drug use, or those who have been taking diazepam or opioid drugs for a long time; 3. Patients whose Mini-Mental State Examination (MMSE) score before surgery determined that they already had PND (such as patients with Alzheimer's disease); 4. Those who have adverse reactions to the anesthetic drugs used; 5. Those with infection at the puncture site and abnormal coagulation function; 6. Those with diabetes and severe organ dysfunction; 7. Those who refuse to participate in any part of this study, such as those who refuse to participate in the scoring of each scale before and after surgery, or those who refuse the anesthesia plan in this study; 8. Those with severe organic lesions (coronary heart disease, second-degree or higher atrioventricular block, bradycardia (HR < 50 beats/min), hypotension (SBP < 90 mmHg), bronchial asthma, severe hypertension, severe blood system dysfunction, liver and kidney function disorders, brain dysfunction, gastric emptying disorder and gastroparesis, patients with significant electrolyte abnormalities)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Barthel index; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale;Frequency of postoperative analgesia administration;Postoperative hospital stay;postoperative nausea and vomiting; | — |
Countries
China
Contacts
Yibin Second People's Hospital