Thyroid disease
Conditions
Interventions
Oliceridine group:Anesthesia induction with oliceridine for thyroid or parathyroid surgery
Sufentanil group:Anesthesia induction with sufentanil for thyroid or parathyroid surgery
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: 1. Under 80 years old; 2. Proposed thyroid or parathyroid surgery; 3. ASA grades I-III.
Exclusion criteria
Exclusion criteria: 1. Difficulty breathing or tracheal compression; 2. Obstructive sleep apnea syndrome; 3. History of neurological disorders such as stroke and epilepsy; 4. Merge severe liver and kidney dysfunction, heart failure, malignant tumors, etc; 5. Long term use of analgesic drugs; 6. Mental illnesses that cannot cooperate with research; 7. Individuals who are allergic to the drugs used in this study; 8. Patients who are pregnant, breastfeeding, or preparing for pregnancy; 9. Has participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of postoperative nausea and vomiting ;Remedial analgesia rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of PONV;Remedial antiemetic rate;Pain numerial rate scale;Hemodynamic events requiring intervention;The incidence of decreased saturation after tracheal extubation;Extubation time;PACU duration and postoperative hospitalization time;Likert scale; | — |
Countries
China
Contacts
Public ContactShen Wang
Shanghai East Hospital
Outcome results
None listed