Metabolic associated fatty liver disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male or female patients aged 18-65 (including those aged 18 and 65); 2. Meets the diagnostic criteria of MAFLD; 3. Baseline liver fat fraction (MRI-PDFF) >= 8% or FibroScan CAP value >259; 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of acute cardiovascular events, or those with a history of coronary angioplasty, stroke, transient ischemic attack, or coronary heart disease; 2. Currently taking medications that may cause steatosis/steatohepatitis (including amiodarone, methotrexate, steroids, tetracycline, tamoxifen, steroids, valproic acid, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes in liver fat fraction compared to baseline after 12 weeks of intervention or at the end of treatment;Changes in liver hardness; | — |
Secondary
| Measure | Time frame |
|---|---|
| The proportion of liver fat fraction decreasing by 30%;Weight, body fat percentage, waist to hip ratio; | — |
Countries
China
Contacts
Beijing Friendship Hospital, Capital Medical University