Primary liver cancer with portal vein thrombosis (CNLC stage IIIa)
Conditions
Interventions
Radiotherapy combined with HAIC treatment group:None
Sponsors
Jiangjin Central Hospital of Chongqing
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria of the "Chinese Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2024 Edition)", which includes enhanced MRI or CT scans of the upper abdomen, and conforms to the "fast in and fast out" enhancement features or liver biopsy for clear diagnosis; 2.Imaging examination confirmed the presence of portal vein thrombosis, consistent with CNLC stage IIIa, and after discussion by a multidisciplinary liver cancer diagnosis and treatment team, it was determined to be unresectable liver cancer; 3.The Child Pugh classification of liver function is A, B, and liver function can significantly improve after liver protection treatment. The liver function reserve test (indocyanine green method) meets the requirements of interventional therapy and radiation therapy; 4.The PS score for the patient's physical condition is 0-1 points; 5.The patient (or family) is fully aware of the treatment plan, risks, and potential risks, and signs an informed consent form;
Exclusion criteria
Exclusion criteria: 1.Patients with extensive and multiple metastases of liver cancer; 2.Child Pugh C liver function, large amount of ascites, severe jaundice, and severe bleeding tendency, which cannot be relieved after treatment; 3.Poor overall condition or cachexia; 4.There are contraindications for chemotherapy and/or radiotherapy, and there is no improvement after treatment; 5.Previously received other treatment plans;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| objective response rate;overall survival; | — |
Countries
China
Contacts
Public ContactHaoyang Tan
Jiangjin Central Hospital of Chongqing
Outcome results
None listed