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A Randomized Controlled Trial of Compound Betamethasone Combined with Ropivacaine Block for Preventing Lateral Femoral Cutaneous Nerve Injury Pain After Total Hip Arthroplasty via the Direct Anterior Approach

A Randomized Controlled Trial of Compound Betamethasone Combined with Ropivacaine Block for Preventing Lateral Femoral Cutaneous Nerve Injury Pain After Total Hip Arthroplasty via the Direct Anterior Approach

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101360
Enrollment
Unknown
Registered
2025-04-24
Start date
2025-04-26
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lateral thigh pain after direct anterior approach (DAA) total hip arthroplasty.

Interventions

Intervention group:Compound betamidate l combined with ropivacaine hydrochloride for lateral femoral cutaneous nerve block
Control group:Ropivacaine hydrochloride for lateral femoral cutaneous nerve block

Sponsors

Sir Run Run Shaw Hospital,Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.>=18 years old. 2. Patients who are scheduled to undergo hip replacement. 3. The first unilateral replacement surgery was performed. 4. Patients with an American Society of Anesthesiologists (ASA) functional status of I-III. 5. Voluntarily participate in this study and sign the informed consent form. If the subjects are unable to read and sign due to reasons such as incapacity for conduct For informed consent forms, or if the subject is a minor, their guardian must act as the agent for the informed process and sign the informed consent form. If the subjects are unable to read the informed consent form (e.g., illiterate subjects), the informed process needs to be witnessed and signed by a witness Informed consent form

Exclusion criteria

Exclusion criteria: 1.Those who already have peripheral neuropathy, such as diabetic peripheral neuropathy, lumbar intervertebral disc protrusion, spinal cord injury, etc. Chronic People with pain syndrome (such as fibromyalgia), those who have been using opioids or glucocorticoids for a long time. Previous surgical history of the hip joint on the surgical side Or a history of trauma (such as after internal fixation of fractures). 2. Those who are known to be allergic to compound betamethasone and ropivacaine. 3. Before the operation, there was pain, numbness or abnormal sensation in the area innervated by the lateral femoral cutaneous nerve (the anterolateral side of the thigh). 4. Vulnerable groups other than the elderly and illiterates include people with mental disorders, those with cognitive impairments, critically ill patients, pregnant women, etc.

Design outcomes

Primary

MeasureTime frame
Pain Score;Hip joint function and activity level;The time when the subjects were able to raise their legs straight for the first time after the operation;Frequency and dosage of rescue analgesia administered in addition to the routine postoperative analgesia regimen.;Quadriceps strength;

Secondary

MeasureTime frame
Postoperative recovery quality;Length of hospitliztion;

Countries

China

Contacts

Public ContactChen Jian

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

3311012@zju.edu.cn+86 137 3819 5538

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026