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Brain Functional Characteristics in Patients with Kinesiophobia Following Anterior Cruciate Ligament Reconstruction: A Cross-Sectional Study

Brain Functional Characteristics in Patients with Kinesiophobia Following Anterior Cruciate Ligament Reconstruction: A Cross-Sectional Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101356
Enrollment
Unknown
Registered
2025-04-24
Start date
2025-04-25
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Anterior Cruciate Ligament Reconstruction with Kinesiophobia

Interventions

ACLR with Kinesiophobia Group:None
ACLR without Kinesiophobia Group:None
Healthy Control Group:None

Sponsors

The Sixth Affiliated Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. ACLR with kinesiophobia group (1) Age 18-45 years; (2) >=6 months after ACLR; (3) Anterior cruciate ligament reconstruction surgery alone or combined with minor meniscal injury, such as a small but stable meniscus tear treated by fixation; (4) TSK-11>11 points; (5) Agree to participate in the study and sign an informed consent form prior to inclusion. 2. ACLR without the kinesiophobia group (1) Age 18-45 years; (2) >=6 months after ACLR; (3) Anterior cruciate ligament reconstruction surgery alone or combined with minor meniscal injury, such as a small but stable meniscus tear treated by fixation; (4) TSK-11=11 points; (5) Agree to participate in the study and sign an informed consent form prior to inclusion. 3. Healthy control group (1) Age 18-45 years; (2) no history of ACL injury; (3) No history of lower limb trauma or other significant illnesses; (4) No use of drugs prior to the study.

Exclusion criteria

Exclusion criteria: 1.History of additional knee surgeries following ACL reconstruction; 2.Ligament injuries in the contralateral leg or recurrent ipsilateral ligament injuries in the affected limb; 3.Severe contralateral knee injuries in the affected limb; 4.Diagnosis of knee osteoarthritis; 5.Pregnancy, planned pregnancy, or women in preparation for conception; 6.Metallic implants in the head, face, or thoracic region; 7.Systemic diseases affecting physical function, neurological/vestibular disorders, movement impairments, or any other conditions/therapies that would compromise study completion.

Design outcomes

Primary

MeasureTime frame
Prefrontal ? wave;Functional connectivity of brain regions;

Secondary

MeasureTime frame
Knee joint motor function;Knee joint function;Psychological preparation for returning to sports;Kinesiophobia;Quality of life;

Countries

China

Contacts

Public ContactYuling Wang

The Sixth Affiliated Hospital, Sun Yat-sen University

wangyul@mail.sysu.edu.cn+86 130 5444 5587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026