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Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Esophageal Carcinoma

Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Esophageal Carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101332
Enrollment
Unknown
Registered
2025-04-23
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Carcinoma

Interventions

Esophageal cancer treated directly with surgery group:None
Esophageal cancer undergoing surgery after neoadjuvant therapy group:None
Esophageal cancer on a wait-and-see strategy after neoadjuvant therapy group:None
Esophageal cancer undergoing radical chemoradiotherapy (or combination immunotherapy) group:None

Sponsors

Xijing Hospital, Air Force Medical University (PLA)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) The age of initial diagnosis is 18-75 years old; 2) Esophageal cancer, with complete case data, clear pathological diagnosis information and staging information; 3) No history of malignant tumors in other parts of the past; 4) There were no metastases in liver, lung or other parts of the imaging examination; 5) Have not received surgery, chemotherapy or radiotherapy, PD-1/PD-L1 immunotherapy before enrollment.

Exclusion criteria

Exclusion criteria: 1) Life expectancy less than 6 months; 2) Patients with no ability to make independent decisions or mental illness; 3) Any other situation that the investigator deems inappropriate to participate in this study.

Design outcomes

Primary

MeasureTime frame
Multi-gene methylation levels;

Secondary

MeasureTime frame
Tumor Markers;Imaging Examinations;

Countries

China

Contacts

Public ContactHong liu

Xijing Hospital, Air Force Medical University (PLA)

hongliu180@126.com+86 137 0928 4513

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026