The Analgesic Effect of the Modified Distal Adductor Canal Block After Total Knee Arthroplasty: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500101317

Enrollment

Unknown

Registered

2025-04-23

Start date

2024-06-13

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain after total knee arthroplasty

Interventions

Experimental Group:Modified Distal Adductor Canal Block

Control Group:Distal Adductor Canal Block

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1: Patients undergoing primary unilateral TKA surgery 2: Age >=18 years, gender not restricted 3: Body mass index (BMI) between 18 and 35 kg/m^2 4: American Society of Anesthesiologists (ASA) classification of I to III 5: Patients who have signed the informed consent form

Exclusion criteria

Exclusion criteria: 1: Presence of moderate or severe knee deformities (varus/valgus deformity >= 30°, flexion deformity >= 30°) 2: Patients undergoing knee revision surgery or with lower limb neuropathy 3: Long-term opioid users (opioid use daily or almost daily for more than 3 months) 4: Patients with language or mental disorders who are unable to complete the Numerical Rating Scale (NRS) for pain assessment 5: Patients with allergies to the drugs used or contraindications to regional blockade

Design outcomes

Primary

Measure	Time frame
Total opioid consumption in the first 24 hours postoperatively;	—

Secondary

Measure	Time frame
Postoperative lower limb muscle strength and knee joint range of motion;The incidence of adverse events, including nausea, vomiting, wound swelling, venous thrombotic events, neurovascular complications, postoperative falls, delirium, admission to the ICU, and death, etc.;Sleep quality on the night of surgery;First time out of bed activity time and hospital day.;Quality of Recovery-15 score;Numerical Rating Scale scores at rest at PACU, 6, 12, 24, 48, and 72 hours postoperatively; Numerical Rating Scale scores during activity at 6, 12, 24, 48, and 72 hours postoperatively.;	—

Measure

Time frame

Postoperative lower limb muscle strength and knee joint range of motion;The incidence of adverse events, including nausea, vomiting, wound swelling, venous thrombotic events, neurovascular complications, postoperative falls, delirium, admission to the ICU, and death, etc.;Sleep quality on the night of surgery;First time out of bed activity time and hospital day.;Quality of Recovery-15 score;Numerical Rating Scale scores at rest at PACU, 6, 12, 24, 48, and 72 hours postoperatively; Numerical Rating Scale scores during activity at 6, 12, 24, 48, and 72 hours postoperatively.;

—

Countries

China

Contacts

Public ContactYang Jing

West China Hospital, Sichuan University

yangjing@wchscu.cn+86 189 8060 2269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026