hemiplegic spasticity after stroke
Conditions
Interventions
Spinal Cord Stimulation (SCS) group:Spinal Cord Stimulation
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 18 and 75 years; 2.A history of a single ischemic or hemorrhagic stroke leading to hemiplegia for more than 6 months (previous strokes that did not result in limb spasticity are excluded); 3.Patients who have not responded to previous systematic rehabilitation therapy; 4.A Modified Ashworth Scale (MAS) score of >= Grade I for the main affected joint of the limb; 5.The research participant or their legal representative has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe illness or medical conditions (including but not limited to cancer, severe cardiac or respiratory diseases, renal failure, and other neurological disorders); 2. Pregnancy or lactation; 3. Receiving antiepileptic drug treatment throughout the study period; 4. No botulinum toxin injection treatment within the past 6 months; 5. Presence of any implanted medical devices; 6. Severe claustrophobia; 7. The clinical physician/investigator considers the joint contracture to be too severe to participate in the study activities; 8. Unwillingness to undergo treatment or follow-up evaluations; 9. Participation in other clinical trials within 3 months prior to enrollment in this clinical trial; 10. Any other conditions deemed by the investigator as unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asworth score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brunnstrom;Assessment of Hemiplegic Hand Function Grading;H-reflex;Brief Pain Inventory;Fugl-Meyer Assessment of Motor Function;Berg Balance Scale;Walking speed 10-m ;EuroQol 5-Dimensions;Hamilton Depression Rating Scale;Hamilton Anxiety Rating Scale;Pittsburgh sleep quality index;Pittsburgh Sleep Quality Index;Resting-State Functional Magnetic Resonance Imaging;Diffusion Tensor Imaging;Brain Metabolic Tomography; | — |
Countries
China
Contacts
Public ContactZhu Hongwei
Xuanwu Hospital Capital Medical University
Outcome results
None listed