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Effects of Dural Puncture Epidural Block at Different Lumbar Interspaces on Labor Analgesia: A Randomized Controlled Trial

Effects of Dural Puncture Epidural Block at Different Lumbar Interspaces on Labor Analgesia: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101309
Enrollment
Unknown
Registered
2025-04-23
Start date
2025-05-17
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor Pain

Interventions

Group L2-3:The dural puncture epidural procedure was carried out at the L2-3 intervertebral space.
Group L3-4:The dural puncture epidural procedure was carried out at the L3-4 intervertebral space.
Group L4-5:The dural puncture epidural procedure was carried out at the L4-5 intervertebral space.

Sponsors

Obstetrics and Gynecology Hospital of Tongji University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Parturients requesting labor analgesia for planned vaginal delivery, aged 20 to 40 years, with ASA I–II, singleton pregnancy, cephalic presentation, primiparous, at 37 to 42 weeks of gestation, experiencing regular uterine contractions with cervical dilation of 2 to 5 cm, and reporting a baseline pain score >=6 on the Numerical Rating Scale (NRS, ranging from 0 to 10; 0 indicating no pain and 10 indicating the worst imaginable pain).

Exclusion criteria

Exclusion criteria: Participants with a body mass index (BMI) >= 40 kg/m², serious pregnancy-related complications (such as cardiac or cerebral dysfunction, hypertensive disorders of pregnancy), contraindications to neuraxial anesthesia, chronic pain conditions, use of other sedatives or analgesics before labor analgesia, or known fetal abnormalities were excluded.

Design outcomes

Primary

MeasureTime frame
onset time to adequate labor analgesia;

Secondary

MeasureTime frame
NRS scores for contraction pain at 1h, 3h, 6h after the initial dose, and at full cervical dilation;times of PCA;ropivacaine consumption per hour;the highest sensory block level during analgesia;sacral sensory block level during the second stage of labor;Bromage score during analgesia;times and dosage of rescue analgesia;

Countries

China

Contacts

Public ContactFang Xin

Obstetrics and Gynecology Hospital of Tongji University

fangxin@51mch.com+86 186 1661 6167

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026