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Comparison of the orthodontic intervention combined with continuous positive airway pressure (CPAP) and the CPAP alone for treating obstructive sleep apnea: a prospective randomized controlled study

Comparison of the orthodontic intervention combined with continuous positive airway pressure (CPAP) and the CPAP alone for treating obstructive sleep apnea: a prospective randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101302
Enrollment
Unknown
Registered
2025-04-23
Start date
2023-03-01
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea syndrome

Interventions

Group A:Digitized orthodontic intervention for malocclusion of misaligned teeth in patients receiving CPAP treatment.
Group A:During the enrollment period, only CPAP treatment was provided, and orthodontic intervention was not performed (considering that the patients included were adults in a late stage of growth and

Sponsors

Hospital of Stomatology, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 69 Years

Inclusion criteria

Inclusion criteria: 1.Aged 20-69 years old; 2.Han nationality, both male and female; 3.Patients diagnosed with malocclusion; 4.Patients diagnosed with obstructive sleep apnea (OSA) through polysomnography (PSG) and anticipated improvement of OSA symptoms; 5.No cognitive impairment; 6.Patients and their family agree to participate in this trial and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with severe heart failure, liver and kidney dysfunction, and systemic infectious diseases; 2.Pregnant and lactating patients; 3.Patients undergoing treatment for other systemic diseases before the start of the study; 4.Participants in other clinical trials during the study; 5.Participants who do not understand or cooperate with the clinical trial.

Design outcomes

Primary

MeasureTime frame
Multi-channel respiratory sleep monitoring results;

Secondary

MeasureTime frame
The the quality of sleep;Sleep snoring, mouth breathing, frequent breath.;

Countries

China

Contacts

Public ContactCao Yang

Hospital of Stomatology, Sun Yat-sen University

caoyang@mail.sysu.edu.cn+86 139 2227 8766

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026