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Comparison of the application of cyclosporine, propofol, and etomidate in painless gastroscopy anesthesia in elderly patients

Comparison of the application of cyclosporine, propofol, and etomidate in painless gastroscopy anesthesia in elderly patients: a single center, prospective, double-blind randomized controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101280
Enrollment
Unknown
Registered
2025-04-23
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The application of different sedatives during gastrointestinal endoscopy includes vital signs such as blood pressure, heart rate, respiration, as well as postoperative adverse reactions in patients, including nausea, vomiting, dizziness, etc

Interventions

Group C:Cipeprofol anesthesia
Group E:Etomidate anesthesia
Group P:Propofol anesthesia

Sponsors

WeiHai Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Elderly patients aged >= 60 who undergo painless gastroscopy examination; 2.Preoperative anesthesia assessment was completed and qualified, with no serious complications such as unstable angina, poor control of severe hypertension, etc; 3.ASA I-III; 4.Sign informed consent form;

Exclusion criteria

Exclusion criteria: 1.Patients with a history of major surgeries, such as cardiac surgery, craniotomy, or other abdominal surgeries; 2.There are contraindications for the use of any drug in research; 3.Allergies to research drugs; 4.Patients with preoperative comorbidities of mental illness or difficulties in understanding, unable to cooperate with follow-up; 5.Patients who have long-term preoperative use of opioid analgesics or psychotropic drugs;

Design outcomes

Primary

MeasureTime frame
vital sign;

Secondary

MeasureTime frame
Adverse reactions;injection pain;fasciculation;

Countries

China

Contacts

Public ContactGuan Yingchao

WeiHai Municipal Hospital

2447547609@qq.com+86 13570977435

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 5, 2026