stroke
Conditions
Interventions
Intervention group:Conventional rehabilitation therapy combined with deep tTIs stimulation
Control group:Conventional rehabilitation therapy combined with deep sham tTIs stimulation
Sponsors
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The first onset of the disease met the diagnostic criteria for cerebral infarction or cerebral hemorrhage stipulated in "Key Points for Diagnosis of Various Major Cerebrovascular Diseases in China" by the Chinese Society of Neurology of the Chinese Medical Association in 2019. (2) Age range: 30 - 75 years old. (3) Stable condition without severe complications. (4) Stroke patients with the first onset within 2 weeks to 6 months after the onset of the disease. (5) All have unilateral upper limb motor dysfunction, at Brunnstrom II - IV stages of the upper limbs. (6) Clear consciousness, able to communicate normally, and can cooperate with rehabilitation treatment. (7) Voluntary participation in this clinical trial and signing the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with unstable vital signs and unable to undergo research; (2) Patients with increased intracranial pressure and acute stroke patients; (3) Patients with metallic implants in the brain, pacemakers or cochlear implants; (4) Patients under deep sedation caused by general anesthetics (such as propofol) or central acting sedatives (such as benzodiazepines, opioids); (5) Patients with frequent arrhythmias and frequent epilepsy; (6) Patients with a history of mental illness, drug abuse and alcoholism; (7) Patients undergoing other neuroregulation treatments (such as transcranial magnetic stimulation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment of Motor Function (FMA-UE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Wolf Motor Function Test Scale (WMFT);Modified Barthel Index, MBI;fMRI;EEG;fNIRS;sEMG; | — |
Countries
China
Contacts
Public ContactMin Su
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
Outcome results
None listed