Mild Cognitive Impairment (MCI)
Conditions
Interventions
Combination group:Acupuncture and adTMS
Single stimulation group:adTMS + sham acupuncture
Sponsors
Nantong Second People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age range of 50-80 years old, meeting the Petersen MCI diagnostic criteria (MoCA score 18-25, MMSE>=24); 2. MRI eliminates structural lesions (cerebral infarction, tumors, and sequelae of cerebral hemorrhage); 3. No history of epilepsy or intracranial metal implants; 4. Voluntarily sign an informed consent form and be able to cooperate in completing traditional Chinese medicine syndrome assessment and follow-up.
Exclusion criteria
Exclusion criteria: 1. Severe depression (HAMD>=17 points) or other mental illnesses (such as schizophrenia); 2. Recently (=2.0 mg/dL, ALT>=3 times the upper limit of normal); 4. Unable to tolerate acupuncture and moxibustion or TMS treatment (such as history of needle fainting and skin allergy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MoCA score change at 12 weeks;MRS-NAA/Cr ratio ;Modified Barthel Index ; | — |
Secondary
| Measure | Time frame |
|---|---|
| P300 latency ; | — |
Countries
China
Contacts
Public ContactXia Jing
Nantong Second People's Hospital
Outcome results
None listed