Grastric cancer
Conditions
Interventions
Observation group:None
Sponsors
China-japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=18 years old, male or female; 2.Patients with gastric cancer confirmed by pathology and imaging, and required neoadjuvant therapy with anti-PD-1 antibody combined with chemotherapy; 3.The presence of initially resectable lesions was assessed by the investigator; 4.Pathological TNM stage: stage II-IVA, cT1-2N1-3M0cT3-4N0-3M0; 5. Patients had not received previous tumor-related treatment including chemotherapy, radiotherapy, and immunotherapy; 6.Patients had not been diagnosed with other malignant tumors, or were diagnosed with malignant tumors but the prognosis was good; 7. Patients can tolerate chemotherapy and immunotherapy 8.ECOG:0-2; 9.The expected survival time was not less than 6 months; 10.Presence of at least one measurable lesion (according to RECIST 1.1 criteria); 11.There were no other primary tumors; 12.Informed consent signed by the patients.
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating woman; 2.Patients have already been enrolled in other clinical trials in the last 6 months; 3.Severe liver dysfunction (Liver function range:TBIL =50 mL/min (Cockcroft-Gault )); 5.Cognitive impairment, mental disorders, poor compliance; 6.Allergic to chemotherapeutic agents; 7.The researchers determined that there were other conditions that were not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate; | — |
Countries
China
Contacts
Public ContactLei Zhou
China-Japan Friendship Hospital
Outcome results
None listed