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Effects of aerobic exercise and Lactobacillus reuteri supplementation on gut microbiota, short-chain fatty acid content and emotional stress of college students

Effects of aerobic exercise and Lactobacillus reuteri supplementation on gut microbiota, short-chain fatty acid content and emotional stress of college students

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101202
Enrollment
Unknown
Registered
2025-04-22
Start date
2025-04-25
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emotional stress

Interventions

Exercise group :Take Lactobacillus reuteri lyophilized powder twice a day , 2 grams each time, for 8 weeks
Sedentary group:Take Lactobacillus reuteri lyophilized powder twice a day , 2 grams each time, for 8 weeks

Sponsors

Shandong Institute of Physical Education
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) The exercise group underwent aerobic exercise at least 3 times a week, each time for at least 30 minutes, and the habit lasted for at least three months; (2) Sedentary group: Total score of Sedentary Behavior Questionnaire (SBQ) >=20; (3) Volunteer to participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Use of various antifungal drugs, antibiotic drugs, immunosuppressive drugs, antipsychotic drugs (including ADHD treatment drugs) and other probiotics, prebiotics, high-dose nutrients and other alternative therapies in the past month; (2) Recent occurrence of severe diarrhea, constipation and other gastrointestinal diseases; (3) Other unstable or serious diseases of the heart, lung, liver, kidney, and hematopoietic system (including unstable angina, uncontrollable asthma, severe allergies, active gastric bleeding, acute leukemia, etc.).

Design outcomes

Primary

MeasureTime frame
DASS-21 psychological self-rating scale; Beck Depression Inventory;

Secondary

MeasureTime frame
Determination of cytokines (IL-6, IL-10, CRP) and serotonin (5-HT), determination of fecal and saliva flora and intestinal short-chain fatty acids;

Countries

China

Contacts

Public ContactJibin Sha

Shandong Institute of Physical Education

shajibin@sdpei.edu.cn+86 182 6418 6520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026