Skip to content

Effect of dexmedetomidine combined with ibuprofen on postoperative pain in children undergoing pediatric urology day surgery: a randomized, controlled, single-blind trial

Effect of dexmedetomidine combined with ibuprofen on postoperative pain in children undergoing pediatric urology day surgery: a randomized, controlled, single-blind trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101201
Enrollment
Unknown
Registered
2025-04-22
Start date
2025-04-28
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases associated with day surgery in pediatric urology

Interventions

opioid-free anesthesia:Anesthesia was induced with dexmedetomidine and ibuprofen
opioid anesthesia:Anesthesia was induced with sufentanil

Sponsors

Children's Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 3 Years

Inclusion criteria

Inclusion criteria: 1. Age 1 to 3 years old, gender is not limited; 2. Pediatric urology day surgery; 3. ASA (American Society of Anesthesiologists) is rated as I~II; 4. The type of surgery is surgery with a < 30min operation time (inguinal oblique hernia, cryptorchidism, hydrocele, varicocele, etc.) 5. The guardian of the child agrees to participate in this clinical study and signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to the anesthetic to be used; 2. History of cardiovascular, respiratory, digestive, central nervous system, liver and kidney diseases; 3. Children with previous surgery; 4. Those who are considered unsuitable by the anesthesiologist and surgeon in charge to participate in the clinical study.

Design outcomes

Primary

MeasureTime frame
The FLACC pain score at the time of awakening from anesthesia;The FLACC pain score measured 2 hours after returning to the ward; The FLACC pain score at 24 hours after the operation;

Secondary

MeasureTime frame
mean arterial pressure;heart rate ;Postoperative adverse events (incidence of nausea and vomiting, delirium, hypoxemia, respiratory depression, etc.);Emergence time; length of stay in resuscitation room; discharge time;

Countries

China

Contacts

Public ContactZhang Li

Children's Hospital of Nanjing Medical University

drzhangli@njmu.edu.cn+86 138 1540 6629

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026