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Study on the intervention effect of low-intensity pulsed ultrasound under ultrasound monitoring on subcutaneous fat hyperplasia caused by insulin injection

Study on the intervention effect of low-intensity pulsed ultrasound under ultrasound monitoring on subcutaneous fat hyperplasia caused by insulin injection

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101171
Enrollment
Unknown
Registered
2025-04-21
Start date
2024-09-12
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subcutaneous fat hyperplasia

Interventions

Test group:Treatment of subcutaneous fat hyperplasia caused by insulin using low-frequency ultrasound therapy device
Control group:On the basis of routine insulin injection health education (one injection, one inch at a time, i.e. no further insulin injection at the LH site, changing the injection site at least one

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with diabetes who meet the diagnostic criteria of WHO in 1999, with insulin injection time = 6 months and subcutaneous fat hyperplasia; 2. Currently, insulin is still being used, and the insulin injection tools used are insulin injection pens and pen needles; 3. Age range from 18 to 75 years old, gender not limited; 4. I voluntarily participate in this trial.

Exclusion criteria

Exclusion criteria: 1. Acute complications such as ketoacidosis, non ketotic hyperosmolar coma, etc; 2. Patients with skin diseases such as lupus, psoriasis, or obvious skin defects/abnormalities (discoloration, tattoos, or other abnormalities) at the site of routine insulin injection, as well as patients with fresh or old abdominal wounds, surgical scars, or other conditions that may affect the results of this study; 3. Merge mental illnesses and uncooperative individuals; 4. Pregnant patients; 5. Patients with progressive malignant tumors or other serious wasting diseases, prone to concurrent infections and bleeding, and those with gastrointestinal organic lesions indicated by endoscopic examination.

Design outcomes

Primary

MeasureTime frame
Changes in the range and skin properties of subcutaneous fat hyperplasia sites on ultrasound imaging;

Countries

China

Contacts

Public ContactRonghui Du

Shanghai Sixth People's Hospital

duronghui2010@163.com+86 185 0166 7682

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026