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Constructing a risk prediction model for early-onset coronary heart disease using a combination of biogenomics and multimodal imaging

Constructing a risk prediction model for early-onset coronary heart disease using a combination of biogenomics and multimodal imaging

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500101164
Enrollment
Unknown
Registered
2025-04-21
Start date
2025-01-25
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature coronary heart disease

Interventions

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with no gender limit, male 18-45 years old, female 18-55 years old, precordial discomfort, chest tightness and other angina pectoris-like symptoms, or those who agree to undergo CCTA can be enrolled; 2. Sign the informed consent form, be able to collect information, conduct medical examinations and retain clinical data as required, and cooperate with follow-up work.

Exclusion criteria

Exclusion criteria: 1. Previous cardiac bypass surgery or other cardiac surgery; 2. Sustained ventricular arrhythmia, myocardial infarction or clearly diagnosed coronary heart disease; 3. Contraindications to CCTA or CAG, including contrast agent allergy, etc.; 4. Severe cardiac, lung, liver, kidney insufficiency, or malignant tumors; 5. Pregnancy.

Design outcomes

Primary

MeasureTime frame
Coronary CTA;Coronary angiography;angiographic microvascular resistance;

Secondary

MeasureTime frame
intravascular ultrasound;Echocardiography;

Countries

China

Contacts

Public ContactTongda Xu

Affiliated Hospital of Xuzhou Medical University

xtd3004@163.com+86 159 9699 0557

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026