Hypertension
Conditions
Interventions
A:10min before anesthesia induction, dexmedetomidine 0.5µg/kg, intravenously pumped.
B:10min before anesthesia induction, dexmedetomidine 1µg/kg, intravenous pump.
C:10min before anesthesia induction, 15ml of 0.9% NaCL injection, intravenous pumping.
Sponsors
Guoyao First Machine Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.The American Association of Anesthesiologists (ASA) grading standard score is grade I - II, and the World Health Organization (WHO) established the diagnostic criteria for hypertension in 1979. Patients with stage I - II hypertension, aged 20-60 years old, plan to undergo elective surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1.ASA >= Grade III; 2.Hypertension stage III; 3.Symptomatic gastroesophageal reflux; 4.Obesity, body surface index (BMI)>30; 5.It is expected that intubation will be difficult; 6.Have myocardial infarction recently; 7.Congestive heart failure; 8.Heart rate < 50 times/min; 9.Cardiac insufficiency; 10.Patients with II - III degree atrioventricular block or cardiac pacemaker implantation; 11.Patients with drug allergy in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters (systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate);Norepinephrine;Epinephrine; | — |
Countries
China
Contacts
Public ContactLiu Yongchen
Guoyao First Machine Hospital
Outcome results
None listed