Type 2 Diabetes Mellitus
Conditions
Interventions
Impaired glucose tolerance (IGT) group:None
Type 2 diabetes mellitus (T2DM) group:None
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 40–80 years old 2. Inclusion of population Healthy individuals: No history of glucose or lipid metabolic abnormalities Impaired glucose tolerance (IGT) group: Diagnosed with glucose intolerance based on medical history or oral glucose tolerance test (OGTT) results Type 2 diabetes mellitus (T2DM) group: Patients with type 2 diabetes and glycated hemoglobin (HbA1c) levels below 8% within the past three months
Exclusion criteria
Exclusion criteria: 1. Acute or chronic infectious or communicable diseases (e.g., fever, pneumonia, urinary tract infection, gastrointestinal infection, COPD, tuberculosis, syphilis, HIV/AIDS) 2. Acute cardiovascular or cerebrovascular diseases (e.g., acute myocardial infarction, heart failure, cerebral hemorrhage, stroke) 3. Liver diseases (e.g., acute or chronic hepatitis) 4. Thyroid disorders (e.g., hyperthyroidism or hypothyroidism) 5. Malignant tumors (e.g., lung, liver, colorectal, or prostate cancer) 6. Severe malnutrition 7. Type 2 diabetes mellitus with significantly elevated blood glucose (HbA1c = 8% within the past three months) 8. Type 2 diabetes with acute complications (e.g., diabetic ketoacidosis or hyperosmolar hyperglycemic state) 9. Type 2 diabetes with diabetic nephropathy (chronic kidney disease stage 3 or higher) 10. Cognitive impairment or dementia 11. Type 1 diabetes mellitus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respiratory quotient;blood glucose;C-Peptide;total cholesterol;triglyceride;High-density lipoprotein cholesterol;Low-density lipoprotein cholesterol;lipoprotein a; | — |
Secondary
| Measure | Time frame |
|---|---|
| resting energy expenditure;photoplethysmography; | — |
Countries
China
Contacts
Public ContactLanlan Wang
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed