Renal insufficiency
Conditions
Interventions
Paravertebral Block Group:Administer 0.05mg/kg of dezocine before the block, followed by T11 paravertebral nerve block
General Anesthesia Group:Anesthesia induction was given midazolam 2 mg, sufentanil 0.15 ug/kg, propofol 2 mg/kg, and vecuronium bromide 0.2 mg/kg. This is followed by laryngeal mask intubation and mec
Local Anesthesia Group:After the sequential method determines the ropivacaine concentration, local infiltration anesthesia is performed with the corresponding concentration of ropivacaine at the incis
Sponsors
Chen Jumei Public Welfare Foundation
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Comply with peritoneal dialysis catheterization surgery, and there are no contraindications to PDC implantation; 2. Age>= 18 years; 3. ASA Class II. ~III; 4. Voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Have severe mental disorder or cognitive impairment; 2. Allergy to the study drug; 3. Contraindications to nerve block anesthesia (abnormal coagulation function, local anesthetic allergy, anatomical abnormalities in the spine or paravertebral region, infection or tumor at the injection site, etc.); 4. Long-term use of non-steroidal or opioid drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-40 on POD1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative VAS scores at rest and during coughing at 1, 4, 8, 12, and 24 hours;Consumption of vasoactive drugs;The changes in hemodynamics of patients at T0, T1, T2, T3, T4, T5, and T6 in different groups.;Preoperative and postoperative levels of IL-6, IL-8, and TNF-a;Preoperative and postoperative levels of CD4+, CD8+, and CD11b;The concentration of ropivacaine 30 minutes and 60 minutes after the use of local anesthetics; | — |
Countries
China
Contacts
Public ContactNiu Zejun
Qingdao University Affiliated Hospital
Outcome results
None listed