Prostatic cancer
Conditions
Interventions
individualized lung open ventilation strategy group:Individualized lung open ventilation strategy
Fixed PEEP group and individualized lung open ventilation strategy group:5cm H2O fixed PEEP
Sponsors
The Second Hospital of Anhui Medical University
Eligibility
Sex/Gender
Male
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients aged 65 years or older undergoing radical prostatic cancer surgery; 2.BMI 18.5~25 kg/m^2; 3.ASA II~III; 4.Moderate and high risk of pulmonary complications (ARISCAT score>=26); 5.Preoperative pulmonary function showed no significant abnormalities, no spinal or thoracic malformations, no difficult airway, asthma, or COPD; 6.The operation time is expected to be >=2h; 7.Volunteer and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Preoperative hypertension was not effectively controlled or poorly controlled (systolic>=180mmHg or diastolic >=110mmHg); 2.Severe respiratory comorbidities (including but not limited to chronic obstructive pulmonary disease, asthma, lung cancer, tuberculosis, etc.); 3.Severe impairment of liver and kidney function; 4.Serious cardiovascular system diseases: such as severe arrhythmia, heart failure, acute coronary syndrome and other underlying diseases; 5.Participated in other clinical studies in the last 3 months; 6.Situations that other researchers found inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary ultrasound score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic index;Pulmonary function index;Arterial blood gas index;Pulmonary complication index;Respiratory mechanical index; | — |
Countries
China
Contacts
Public ContactLi Yun
The Second Hospital of Anhui Medical University
Outcome results
None listed