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Clinical randomized controlled study on the improvement effect of probiotics on atopic dermatitis in children

Clinical randomized controlled study on the improvement effect of probiotics on atopic dermatitis in children

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101103
Enrollment
Unknown
Registered
2025-04-21
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis in children

Interventions

Control group:None
Placebo group:Conventional treatment +TCS/TCI, combined with oral placebo
Probiotic group:Conventional treatment +TCS/TCI, combined with oral probiotic

Sponsors

The Second People's Hospital of Jingdezhen
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Children aged 6 months to 5 years who meet the pediatric standard diagnosis of atopic dermatitis have normal weight and height. 2. The patients are generally in good condition and have no other serious heart, lung, kidney, liver dysfunction and metabolic diseases. 3.No antibiotics or other drugs or probiotics were used in the first 3 months after the completion of treatment.

Exclusion criteria

Exclusion criteria: 1.Patients who did not meet the inclusion criteria. 2.Have a severe active viral or bacterial infection that is not controlled by treatment. .3Have any other serious or chronic medical conditions that the investigator believes may affect the patient's treatment, follow-up, or evaluation. It includes any uncontrolled and clinically significant neurological, psychiatric, immune-regulatory, metabolic and infectious diseases. 4. Patients who are not suitable for probiotic-assisted therapy after diagnosis and evaluation by clinicians.

Design outcomes

Primary

MeasureTime frame
Routine blood results;Serum IgE;Serum IgG;composition of gut microbiota;

Countries

China

Contacts

Public ContactXuewei Lei

The Second People's Hospital of Jingdezhen

13879806471@163.com+86 138 7980 6471

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026