Neural Mechanisms of Encephaloduroarteriosynangiosis in Enhancing Cognitive Function in Patients with Intracranial Arterial Stenosis and Occlusion

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500101085

Enrollment

Unknown

Registered

2025-04-20

Start date

2025-04-20

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

moyamoya disease

Interventions

Group of encephaloduroarteriosynangiosis:None

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (i) aged 18-65 years; (ii) patients diagnosed with moyamoya disease who are considering EDAS surgery after evaluation by two neurosurgeons have expressed intent to proceed with EDAS surgery; (iii) Fazekas scores <= 2.

Exclusion criteria

Exclusion criteria: (i) Neurological disorders, except TIA; (ii) Psychiatric illnesses; (iii) Below-normal intelligence or severe cognitive impairment preventing cognitive assessment; (iv) Systemic immune diseases; (v) History of head trauma, substance abuse, or alcohol abuse; (vi) Serious physical illnesses; (vii) Pregnancy; (viii) Contraindications for magnetic resonance scanning

Design outcomes

Primary

Measure	Time frame
Mini-mental State Examination,MMSE;;;	—

Countries

China

Contacts

Public ContactXingwen Zhang

The First Medical Center, Chinese PLA General Hospital

13707562@qq.com+86 189 1178 9817

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026