Patients with Gastrointestinal Tumors in Peripheral Neuropathy Induced by Pain Chemotherapy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with histological or pathological diagnosis of digestive tract tumors. 2. Age >= 18 years old; 3. The chemotherapy regimen is paclitaxel or platinum neurotoxic chemotherapy drugs and subsequent chemotherapy requires at least 3 cycles; 4. According to the Total Neuropathy Score clinical version (TNSc) score > 0 and DN4 score >= 4 points; 5. Evaluated by the Physical Status Scale (ECOG), those with a score of = 41 were included in the study. 7. Possessing complete cognitive comprehension. 8. Informed consent to and voluntary participation in this study. 9. Patients can and do use electronic devices.
Exclusion criteria
Exclusion criteria: 1. Concomitant with diabetes, peripheral vascular disease, hypothyroidism, renal insufficiency, vitamin B12 deficiency, and neurological diseases (including stroke, Parkinson's disease, multiple sclerosis, and dementia); 2. The condition is critical; 3. Combined with other cancers, cancer brain metastases, craniocerebral trauma, mental illness, neurodegenerative diseases; 4. Patients receiving concurrent radiotherapy; 5. Those with exercise contraindications, such as lower extremity venous thrombosis and limited limb function; 6. Received or prepared for other interventions within 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS;CIPN symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Balanced capacity;Objective limb function test;Living quality;Exercise self-efficacy;exercise intensity;physical activity; | — |
Countries
China
Contacts
Jiangnan University Hospital; Jiangnan University