Crohn's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Crohn's disease was definitively diagnosed according to the diagnostic criteria of the Chinese Guidelines for the Diagnosis and Treatment of Crohn's Disease (2023-Guangzhou); 2.Patients have ultrasound endoscopy (EUS), transabdominal intestinal ultrasound (IUS) results and data records, serum specimens, and complete clinical information; 3.Patients may sign an informed consent form; 4.Peripheral blood specimens were collected from healthy individuals as a healthy control group;
Exclusion criteria
Exclusion criteria: 1.Patients who have undergone previous bowel resection; 2.Combination of intestinal tumors, intestinal tuberculosis and intestinal infections; 3.Combination of other autoimmune diseases;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EUS lesion intestinal wall thickness;The thickness of the intestinal wall from the mucosal to serosal surface under the IUS;C-X-C motif chemokine ligand 8;Blood flow in the intestinal wall under the IUS;Whether the layers of the intestinal wall under the IUS were changed;Whether mesenteric fat was hyperplastic under the IUS;Monocyte chemotactic protein-1;Tumor necrosis factor-like cytokine 1A; | — |
Countries
China
Contacts
Zhongshan Hospital Affiliated to Xiamen University