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Use of plasmatrix membrane coverage to promote soft tissue regeneration during simultaneous guided bone regeneration during implant placement

Use of plasmatrix membrane coverage to promote soft tissue regeneration during simultaneous guided bone regeneration during implant placement

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101049
Enrollment
Unknown
Registered
2025-04-18
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental defect

Interventions

control group:Resorbable Collagen Membrane placement for Simultaneous Guided Bone Regeneration during Implant Placement
Experimental group:Resorbable Collagen Membrane and plasmatrix membrane placement for Simultaneous Guided Bone Regeneration during Implant Placement

Sponsors

hospital of stomatology wuhan university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1, A single missing tooth with two adjacent natural teeth still present 2, No vertical bone loss 3, Favorable bone defects clinically assessed as Class 0 and Class II (Hämmerle, 2014), with a bone volume that ensures that the implant gains initial stability and that the implant is not exposed by more than one third. 4, Subjects volunteered to participate in the trial and signed a written informed consent form

Exclusion criteria

Exclusion criteria: 1, Inability to undergo surgery due to systemic reasons, such as high blood pressure, diabetes, etc. 2, Untreated dental disease in neighboring teeth 3,Uncontrolled periodontal conditions and poor oral hygiene 4, Heavy smokers (>10 cigarettes per day)

Design outcomes

Primary

MeasureTime frame
early healing index;

Secondary

MeasureTime frame
Visual analogue scoring;Early soft tissue keratinization;Postoperative edema/swelling;soft tissue augmentation;bone augmentation;mucasol scarring index;

Countries

China

Contacts

Public ContactYun Qiu

hospital of stomatology wuhan university

qiuyun@whu.edu.cn+86 133 8751 9411

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026