Hemiplegia
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age 18-75 years old (including boundary value); Unilateral limb paralysis due to clinical diagnosis of stroke, traumatic brain injury or brain tumor (course of >=6 months); Fugl-Meyer Upper Extremity Motor Function Score (FMA-UE) <=40 points; Modified Ashworth Spasm Score (MAS) <=3; Sign the informed consent form, voluntarily participate in the study and cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: Absolute exclusions: (1) Presence of spinal cord injury or peripheral neuropathy; (2) Skin infection or systemic active infection at the implantation site; (3) Severe cardiopulmonary insufficiency (NYHA cardiac function class>=grade III or FEV11.5 or platelet <80×10?/L)¹; (5) Pregnant or lactating females. Relative exclusions: (1) cognitive dysfunction (MMSE score< 24 points); (2) Previous spinal cord or deep brain stimulation surgery; (3) Combined with other neurodegenerative diseases (such as Parkinson's disease, ALS, etc.); (4) Other conditions judged by the investigator to be inappropriate for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FMA-UE (Fugl-Meyer) motor function score; | — |
Secondary
| Measure | Time frame |
|---|---|
| FMA-UE (Fugl-Meyer) motor function score;Spasm Rating Scale (modified Ashworth method);Somatosensory Evoked Potentials of Upper and Lower Limbs;Motor-evoked Potentials of Upper and Lower Limbs;Electromyography Test;Electroencephalogram; | — |
Countries
China
Contacts
Public ContactChongjie Cheng
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed