first-episode schizophrenia
Conditions
Interventions
Risperidone treatment normal weight group:Adults 2 times daily. Start with 1mg/day and gradually increase the dose to 2mg/day over a 1-week period
Gradually increase to 6 mg daily over 2 weeks. Therea
Risperidone treatment weight gain group:Adults 2 times daily. Start with 1mg/day and gradually increase the dose to 2mg/day over a 1-week period
Gradually increase to 6 mg daily over 2 weeks. Thereaft
Sponsors
Nantong Fourth People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with first-episode schizophrenia, meeting the DSM-5 criteria; 2.Ages between 18 and 65 years old; 3.Have not recently received other antipsychotic medication treatments; 4.Voluntarily participate in the study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with underlying chronic diseases; 2.Patients currently or previously diagnosed with substance use disorder, intellectual disability, autism spectrum disorder, dementia, or severe cognitive impairment according to DSM-5 criteria; 3.Patients who are in the preconception or breastfeeding period; 4.Patients taking other types of medication;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hormones: Prolactin, Thyroid hormones, Cortisol; | — |
Countries
China
Contacts
Public ContactNing Shen
Nantong Fourth People’s Hospital
Outcome results
None listed