non-small cell lung cancer
Conditions
Interventions
EGFR-TKI resistance group:Radiotherapy
Stereotactic Radiotherapy Group:Radiotherapy
Superfractionated Pulsed Radiotherapy Group:Radiotherapy
Hypofractionated Radiotherapy Group:Radiotherapy
Conventional Fractionated Radiotherapy Group:Radiotherapy
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Non-small cell lung cancer confirmed by histopathological examination; 2. The number of metastases is greater than 3; 3. No brain metastases or stable lesions; 4. Negative driver genes (including EGFR, ALK, ROS, BRAF, MET, RET); 5. PS 0-1 points, estimated survival > 3 months; 6. Age 18-75 years old; 7. Adopt PET-CT assessment (including FDG and FMISO, not mandatory); 8. No contraindications to immunotherapy and radiotherapy; 9. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Severe dysfunction of vital organs (heart, liver, kidney); 2.Presence of other malignant tumors; 3.Uncontrolled cardiac disease or myocardial infarction within the last 6 months; 4.History of mental illness; 5.Any other conditions deemed unsuitable for participation in the study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distant Lesion Response Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence rate of immunotherapy-related adverse reactions;Overall survival;Progression-free survival; | — |
Countries
China
Contacts
Public ContactJianguo Sun
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed