None
Conditions
Interventions
Transverse fascia plane combined with posterior sheath block of rectus abdominis (block group):Patients in the block group underwent ultrasound-guided bilateral transversal plane block combined with p
Incision local infiltration group(incision group):Patients in the incision group were subjected to local infiltration by surgeons, and the injection dosage of local anesthetics was as follows: in the
Sponsors
Zhongshan Hospital(Xiamen), Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. It is planned to undergo four-port laparoscopic gynecological surgery in Xiamen Hospital, Zhongshan Hospital affiliated to Fudan University, including laparoscopic total hysterectomy, laparoscopic total hysterectomy, unilateral (double) adnexectomy and laparoscopic oophorectomy. 2. Patients aged 18-75 years. 3. The anesthesia method is compound anesthesia, that is, general anesthesia combined transverse plane abdominis combined with rectus abdominis sheath block or general anesthesia combined with local incision infiltration. 4. American Standards Association (ASA) grade I.-III. before surgery. 5. Those who voluntarily participate in this clinical study.
Exclusion criteria
Exclusion criteria: 1. Those who are unable to cooperate, communicate, and make an accurate assessment of their own pain; 2. Patients with liver and kidney insufficiency; 3. Allergy to bupivacaine liposomes or bupivacaine; 4. Have a history of chronic pain, a history of opioid abuse in the past, and a history of long-term alcohol consumption; 5. Severe hemodynamic instability, serious underlying diseases and other disorders; 6. Those who refuse to use analgesic pumps; 7. Patients with anxiety, depression and other psychological diseases before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative opioid consumption in the 72h post-operative period, calculated as morphine equivalent.; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS scores at rest and exercise 2h, 6h, 12h, 24h, 48h, 72h after surgery;Quality of sleep on the night of surgery;Quality of recovery at 24h, 48h, and 72h;The time of the patient's first outbreak of pain, and the clinician's remedy for the pain;The occurrence of adverse anesthetic reactions within 3 days after surgery;Patient's first time out of bed activity;Total length of stay;Drain extraction time; | — |
Countries
China
Contacts
Public ContactZhiyao Wang
Zhongshan Hospital, Fudan University; Zhongshan Hospital(Xiamen), Fudan University
Outcome results
None listed