glaucoma
Conditions
Interventions
Gold Standard:(1) glaucomatous optic neuropathy (2) retinal nerve fiber layer (RNFL) defect corresponds to visual field defect.
Index test:a precise diagnosis and clinical decision system for glaucoma based on multi-modal large language model
Sponsors
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Glaucoma: 1. age >=18 years; 2. Complete fundus photographs, VF, OCT reports 3. glaucoma optic neuropathy, which must meet the following diagnostic criteria: (1) glaucomatous optic neuropathy (cup-to-disc ratio =0.7, and/or binocular C/D difference greater than 0.2, and/or supratemporal and infratemporal discs perpendicular to the width of less than or equal to 0.1 optic discs, and/or RNFL defects, and/or bleeding of optic discs, and/or local incisal disc formation); (2) retinal nerve fiber layer (RNFL) defect corresponds to visual field defect. 4. The patient has at least two consecutive reliable visual field test results. 5. Patients voluntarily participated in the study and signed informed consent; Non-glaucoma: 1. age >=18 years; 2. Complete fundus photos, VF, OCT report 3. patients without glaucomatous optic neuropathy; 4. The patient voluntarily participates in this study and signs an informed consent form;
Exclusion criteria
Exclusion criteria: 1.Glaucoma and non-glaucoma: a. Unreliable visual field test results with one of the following: (1) fixation loss rate >=20% (2) false-positive rate >=15% (3) false-negative rate >=33% 2. History of intraocular surgery or ocular trauma; 3. Severe opacity of cornea or interstitial refraction; 4. There are various types of fundus diseases affecting the collection of eye parameters or interfering with visual field detection; 5. Complicated with severe systemic disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area Under the ROC Curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rationality of the glaucoma differential diagnosis based on the large language model diagnostic system and physicians' trust in the system.;Specificity;Sensitivity; | — |
Countries
China
Contacts
Public ContactFei Li
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Outcome results
None listed