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The impact of sub-anesthetic dose of esketamine on postoperative pain and anxiety after Kyphoplasty

The impact of sub-anesthetic dose of esketamine on postoperative pain and anxiety after Kyphoplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500101003
Enrollment
Unknown
Registered
2025-04-17
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-vertebralplasty

Interventions

Control group:After the patient was positioned, sterilized, sterile surgical sheets were laid, and the anesthesiologist attached a Mindray monitor to monitor vital signs. The surgeon used 1% lidocaine
Experimental group:After the patient was positioned, sterilized, sterile surgical sheets were laid, and the anesthesiologist attached a Mindray monitor to monitor vital signs. At the same time, 0.25mg

Sponsors

Huaian 82nd Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Patients with PVP indication and consent to surgery; (2) American Society of Anesthesiology (ASA) Class I-320 patients; (3) A history of osteoporosis prior to fracture and a fresh vertebral compression fracture; (4) fracture without symptoms of nerve or spinal cord compression; (5) Definite diagnosis in imaging data;

Exclusion criteria

Exclusion criteria: (1) preoperative cognitive dysfunction, delirium and a history of psychiatric disorders, inability to communicate and do not cooperate with the anesthesia operator; (2) recent use of anesthesia related analgesia, sedation and antidepressant drugs; (3) Uncontrolled hypertension, increased intracranial pressure, intracranial space occupying lesions, glaucoma, hyperthyroidism, long-term alcoholism; (4) Infection or allergy to the drug at the intended puncture site; (5) Other orthopedic diseases.

Design outcomes

Primary

MeasureTime frame
VAS;

Secondary

MeasureTime frame
SAS;SDS;ODI;OAA/S;

Countries

China

Contacts

Public ContactThe impact of sub-anesthetic dose of esketamine on postoperative pain and anxiety after Kyphoplasty

Huaian 82nd Hospital

214976006@qq.com+86 152 6179 5539

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026